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JWH-018 (1-pentyl-3-(1-naphthoylindole) or AM-678 is an analgesic chemical from the naphthoylindole family. It acts as a full agonist at both the CB₁ and CB₂ cannabinoid receptors, with some selectivity for CB₂. It produces effects in animals similar to those of tetrahydrocannabinol (THC), a cannabinoid naturally present in cannabis. This leads to its use in synthetic cannabis products that in some countries are sold legally as “incense blends”. Buy JWH-018 Online

JWH 018 is a mildly selective agonist of the peripheral cannabinoid (CB2) receptor, derived from the aminoalkylindole WIN 55,212-2. The Ki values for binding central cannabinoid (CB1) and CB2 receptors are 9.0 and 2.94 nM, respectively, for a CB1:CB2 ratio of 3.06.1 Its effects on suppression of spontaneous activity, maximum possible antinociceptive effect in the tail-flick assay, and rectal temperature are comparable to those of WIN 55,212-2 when tested in rats.

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You can Buy JWH-018 Online from Ketcoc and get many great deals. Before going to order it online, it is good to know more about the drug in question. Just like any other drug, JWH 018 is not without physical and psychological effects. Some adverse effects have been reported from JWH-018 use. One study reported psychotic relapses and anxiety symptoms in well-treated patients with mental illness following the inhalation. Due to concerns about the potential of cannabinoids. And other synthetic cannabinoids to cause psychosis in vulnerable individuals, it has been recommended that people with risk factors for psychotic illnesses (like a past or family history of psychosis) not use these substances. Order JWH-018 Effects from Ketcoc and get the best quality high grade product.

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